Regression of symptoms after selective iron chelation therapy in a case of neurodegeneration with brain iron accumulation
Identifieur interne : 002652 ( Main/Exploration ); précédent : 002651; suivant : 002653Regression of symptoms after selective iron chelation therapy in a case of neurodegeneration with brain iron accumulation
Auteurs : Gian Luca Forni [Italie] ; Manuela Balocco [Italie] ; Laura Cremonesi [Italie] ; Giovanni Abbruzzese [Italie] ; Roberto Carlo Parodi [Italie] ; Roberta Marchese [Italie]Source :
- Movement Disorders [ 0885-3185 ] ; 2008-04-30.
English descriptors
- KwdEn :
- Aged, 80 and over, Brain (metabolism), Brain (pathology), Dyskinesias (drug therapy), Dyskinesias (pathology), Female, Humans, Iron (metabolism), Iron Chelating Agents (therapeutic use), Magnetic Resonance Imaging, NBIA, Nerve Degeneration (drug therapy), Nerve Degeneration (pathology), Treatment Outcome, deferiprone, iron chelation.
- MESH :
- chemical , metabolism : Iron.
- drug therapy : Dyskinesias, Nerve Degeneration.
- metabolism : Brain.
- pathology : Brain, Dyskinesias, Nerve Degeneration.
- chemical , therapeutic use : Iron Chelating Agents.
- Aged, 80 and over, Female, Humans, Magnetic Resonance Imaging, Treatment Outcome.
Abstract
We report the results of iron chelating treatment with deferiprone in a 61‐year‐old woman with signs and symptoms of neurodegeneration with brain iron accumulation (NBIA). After 6 months of therapy the patient's gait had improved and a reduction in the incidence of choreic dyskinesias was observed. Her gait returned to normal after an additional 2 months of therapy, at which time there was a further reduction in involuntary movements and a partial resolution of the blepharospasm. © 2008 Movement Disorder Society
Url:
DOI: 10.1002/mds.22002
Affiliations:
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After 6 months of therapy the patient's gait had improved and a reduction in the incidence of choreic dyskinesias was observed. Her gait returned to normal after an additional 2 months of therapy, at which time there was a further reduction in involuntary movements and a partial resolution of the blepharospasm. © 2008 Movement Disorder Society</div></front></TEI><affiliations><list><country><li>Italie</li></country><region><li>Lombardie</li></region><settlement><li>Milan</li></settlement></list><tree><country name="Italie"><noRegion><name sortKey="Forni, Gian Luca" sort="Forni, Gian Luca" uniqKey="Forni G" first="Gian Luca" last="Forni">Gian Luca Forni</name></noRegion><name sortKey="Abbruzzese, Giovanni" sort="Abbruzzese, Giovanni" uniqKey="Abbruzzese G" first="Giovanni" last="Abbruzzese">Giovanni Abbruzzese</name><name sortKey="Balocco, Manuela" sort="Balocco, Manuela" uniqKey="Balocco M" first="Manuela" last="Balocco">Manuela Balocco</name><name sortKey="Cremonesi, Laura" sort="Cremonesi, Laura" uniqKey="Cremonesi L" first="Laura" last="Cremonesi">Laura Cremonesi</name><name sortKey="Marchese, Roberta" sort="Marchese, Roberta" uniqKey="Marchese R" first="Roberta" last="Marchese">Roberta Marchese</name><name sortKey="Parodi, Roberto Carlo" sort="Parodi, Roberto Carlo" uniqKey="Parodi R" first="Roberto Carlo" last="Parodi">Roberto Carlo Parodi</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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